Skip to content
Mads TimmermannSkincare specialist
Skin science

Free radicals

Also called: Reactive oxygen species, ROS

Free radicals are unstable molecules that can damage skin lipids, proteins, and DNA when oxidative stress overwhelms the skin's normal defences. Antioxidants and sunscreen help reduce that stress.

At a glance

  • UV exposure is a major everyday source of oxidative stress in skin.
  • Antioxidants support sunscreen; they do not replace it.
  • Vitamin C, vitamin E, ferulic acid, and green tea are common antioxidant ingredients.
On this page

The short answer

Free radicals are unstable molecules. In skin, too much oxidative stress can damage lipids, proteins, and DNA, which is why sunscreen and antioxidants come up so often in pigmentation and ageing conversations.

The useful skincare translation is simple: protect in the morning, repair gently at night, and do not expect one antioxidant serum to act like a tiny security guard with a clipboard.

Why free radicals matter

UV exposure is one major source of oxidative stress in skin. A vitamin C review[1] explains that vitamin C contributes to antioxidant protection and collagen biology in skin, while also noting how exposure and deficiency can affect skin health.

Topical antioxidants can add support. A 2003 study[2] found that combined topical vitamin C and vitamin E improved UV photoprotection compared with either antioxidant alone. That does not mean antioxidants replace broad-spectrum sunscreen. It means they can sit beside it.

What to do with this term

If a product says "fights free radicals," read it as antioxidant support, not magic repair.

Useful antioxidant ingredients include l-ascorbic acid, tocopherol, ferulic acid, and green tea extract. The calm routine is still the same: cleanse gently, use a moisturiser your skin tolerates, apply SPF every morning, and avoid turning antioxidant shopping into a second job.

Keep reading

Common questions

Do antioxidants stop free radicals?

They help neutralise some oxidative stress, but no topical antioxidant blocks every free radical. Sunscreen and sensible sun behaviour still matter.

Are free radicals always bad?

No. The body uses reactive molecules in normal biology. Skin problems arise when oxidative stress exceeds what the skin can comfortably handle.

Get Mads's weekly skincare brief

Evidence-led guides, ingredient deep-dives, and routines that actually work. No fluff.

Free. Unsubscribe any time. We never share your email.

Citations

  1. Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866. - PMID 28805671
  2. Lin JY, et al. UV photoprotection by combination topical antioxidants vitamin C and vitamin E. J Am Acad Dermatol. 2003;48(6):866-874. - PMID 12789176